Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ARG1 | P05089 | 5/20 | 0.46 |
| ▸ | ARG2 | P78540 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894636 | 0.88 | ARG1 (0.63) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895725 | 0.87 | ARG1 (0.62) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL28256810 | 0.81 | KCNH2 (0.47) | KCNH2ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20156728 | 0.81 | ARG1 (0.56) | ARG1ARG2 | |
| SCHEMBL10265570 | 0.80 | PRMT3 (0.51) | SLC6A2SLC6A3ARG1ARG2 | |
| SCHEMBL12292360 | 0.80 | ARG1 (0.63) | ARG1ARG2 | |
| SCHEMBL20156732 | 0.79 | CCR3 (0.48) | ARG1ARG2 | |
| SCHEMBL894944 | 0.78 | ARG1 (0.67) | ARG1ARG2 | |
| SCHEMBL895202 | 0.78 | ARG1 (0.63) | ARG1ARG2 | |
| SCHEMBL19055962 | 0.77 | ARG1 (0.61) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089490-A1 | ARGINASE INHIBITOR COMBINATION THERAPIES | CALITHERA BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |