Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140770 | 0.79 | ALDH1A1 (0.51) | HTR7KDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL20141745 | 0.78 | DRD4 (0.49) | HTR7KDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL20140902 | 0.77 | HTR7 (0.48) | HTR7KDM4EALDH1A1ALOX15TSHR | |
| SCHEMBL20139955 | 0.75 | KDM4E (0.52) | HTR7KDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL20141481 | 0.74 | KDM4E (0.51) | HTR7KDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL20140044 | 0.74 | MTOR (0.54) | HTR7KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL20140720 | 0.73 | MTOR (0.57) | KDM4EALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL2328515 | 0.73 | DRD4 (0.59) | HTR7DRD2DRD4DRD3CHRM4 | |
| SCHEMBL20140731 | 0.72 | DRD4 (0.54) | HTR7KDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL20156863 | 0.71 | DRD4 (0.53) | HTR7KDM4EALDH1A1ALOX15DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |