Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141481 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| SCHEMBL20140044 | 0.89 | MTOR (0.54) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| SCHEMBL20157519 | 0.88 | DRD4 (0.49) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| SCHEMBL20140202 | 0.85 | HTR7 (0.55) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| SCHEMBL20156931 | 0.85 | MTOR (0.51) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| SCHEMBL20140126 | 0.84 | MTOR (0.53) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL20140648 | 0.84 | PRMT5 (0.42) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL20140770 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1NPSR1DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL20140671 | 0.83 | MTOR (0.52) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL20142175 | 0.83 | GRM1 (0.50) | KDM4EALDH1A1NPSR1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |