Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141564 | 0.92 | MTOR (0.43) | MEN1KMT2AHCRTR2MTORRPTOR | |
| SCHEMBL20141561 | 0.92 | MTOR (0.43) | MEN1KMT2AHCRTR2MTORRPTOR | |
| SCHEMBL20156998 | 0.83 | MTOR (0.43) | MEN1KMT2AHCRTR2MTORRPTOR | |
| SCHEMBL20141589 | 0.83 | MTOR (0.43) | MEN1KMT2AHCRTR2MTORRPTOR | |
| SCHEMBL20141592 | 0.83 | MTOR (0.43) | MEN1KMT2AHCRTR2MTORRPTOR | |
| SCHEMBL20156826 | 0.82 | MTOR (0.46) | MEN1KMT2AMTORRPTORMLST8 | |
| SCHEMBL20140773 | 0.79 | MTOR (0.49) | MTORRPTORMLST8LMNAGAA | |
| SCHEMBL20157149 | 0.76 | MTOR (0.39) | MEN1KMT2AMTORRPTORMLST8 | |
| SCHEMBL20141016 | 0.75 | MTOR (0.53) | MEN1KMT2AMTORRPTORMLST8 | |
| SCHEMBL20157035 | 0.73 | NPC1 (0.46) | MEN1KMT2AMTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |