Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140151 | 0.88 | MTOR (0.41) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20140317 | 0.82 | MTOR (0.49) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20141545 | 0.82 | MTOR (0.49) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20156836 | 0.78 | MTOR (0.42) | ALDH1A1MTORRPTORMLST8KDM4E | |
| SCHEMBL20156993 | 0.75 | MTOR (0.37) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20140350 | 0.74 | MTOR (0.54) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20140147 | 0.71 | MTOR (0.47) | ALDH1A1MTORRPTORMLST8MAPT | |
| SCHEMBL20156915 | 0.70 | LMNA (0.33) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL20141003 | 0.70 | MTOR (0.54) | ALDH1A1MTORRPTORMLST8HTT | |
| SCHEMBL20140926 | 0.70 | MTOR (0.54) | ALDH1A1MTORRPTORMLST8HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |