Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157327 | 0.79 | — | — | |
| SCHEMBL20157051 | 0.79 | KDM4E (0.36) | ALDH1A1 | |
| SCHEMBL20156916 | 0.77 | — | — | |
| SCHEMBL20156915 | 0.76 | LMNA (0.33) | ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL20156838 | 0.75 | ALDH1A1 (0.39) | MTORRPTORMLST8ALDH1A1MAPT | |
| SCHEMBL20157268 | 0.75 | MTOR (0.39) | MTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20156836 | 0.75 | MTOR (0.42) | MTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20140350 | 0.75 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1MAPT | |
| SCHEMBL20157533 | 0.75 | — | — | |
| SCHEMBL20157213 | 0.74 | MTOR (0.41) | MTORRPTORMLST8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |