Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075401 | 0.78 | AHR (0.56) | AHRGRM5HTR2AHTR2CHTR2B | |
| SCHEMBL20129632 | 0.76 | AHR (0.50) | HTR7AHRHTR1ADRD2DRD4 | |
| SCHEMBL22187963 | 0.75 | MTOR (0.47) | HTR7GRM5DRD2DRD4DRD3 | |
| SCHEMBL20139979 | 0.74 | MTOR (0.47) | HTR7HTR1ADRD2DRD4DRD3 | |
| SCHEMBL20139917 | 0.74 | AHR (0.45) | AHRGRM5HTR1AADRA1AADRA1B | |
| SCHEMBL3088832 | 0.72 | DRD4 (0.54) | HTR7GRM5HTR1AADRA1AADRA1B | |
| SCHEMBL20129629 | 0.68 | CRBN (0.53) | NAMPT | |
| SCHEMBL6949464 | 0.68 | AR (0.46) | GRM5DRD2DRD4DRD3NAMPT | |
| SCHEMBL2077261 | 0.68 | ADRA2C (0.56) | HTR7GRM5HTR1AADRA1AADRA1B | |
| SCHEMBL22904443 | 0.68 | HTR1A (0.54) | HTR7GRM5HTR1AADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |