Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739313 | 0.75 | HPGD (0.51) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14927059 | 0.72 | HPGD (0.46) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL509140 | 0.67 | HPGD (0.54) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL509560 | 0.65 | CYP1A2 (0.54) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6648687 | 0.65 | ALDH1A1 (0.51) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1034975 | 0.65 | HPGD (0.49) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7225379 | 0.65 | HPGD (0.49) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10082156 | 0.65 | USP2 (0.57) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL509845 | 0.64 | HPGD (0.58) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| Methylamine SCHEMBL11580647 | 0.64 | HPGD (0.47) | HPGDMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |