Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14927059 | 0.81 | HPGD (0.46) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL509560 | 0.80 | CYP1A2 (0.54) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL509845 | 0.79 | HPGD (0.58) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL509140 | 0.79 | HPGD (0.54) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL471656 | 0.77 | HPGD (0.50) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL471665 | 0.76 | HPGD (0.72) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1034975 | 0.76 | HPGD (0.49) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6648687 | 0.76 | ALDH1A1 (0.51) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13666585 | 0.76 | HPGD (0.49) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10082156 | 0.76 | USP2 (0.57) | HPGDLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829741-B2 | Process for producing α, α-difluoroamine | NATIONAL UNIVERSITY CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1813596-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE | National University Corporation Hokkaido University (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | FUCA1, FUCA2, DBH | HPGD 1246/4885LMNA 4155/4885MEN1 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.