SCHEMBL509845

SCHEMBL509845

CCN(CC)C(=O)c1ccc(C)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
MEN1 O00255 1/20 0.58
LMNA P02545 1/20 0.58
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 1/20 0.54
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.47
HSP90AA1 P07900 6/20 0.45
HSP90AB1 P08238 6/20 0.45
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TAS1R2 Q8TE23 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HSD11B1 P28845 1/20 0.43
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509140 0.85 HPGD (0.54) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL12213211 0.84 SMN1; SMN2 (0.50) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL471656 0.84 HPGD (0.50) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL2170651 0.82 HPGD (0.57) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL13666585 0.82 HPGD (0.49) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL471670 0.82 HPGD (0.51) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL471668 0.82 HPGD (0.51) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL18570098 0.80 HSP90AA1 (0.64) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL9171117 0.80 MEN1 (0.52) HPGDSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL1536288 0.80 HTT (0.55) HPGDSMN1; SMN2MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11883650-B1 Bi-layered neural interface with nerve-facing drug eluting structure Verily Life Sciences, LLC (US) 2024-01-30 US claimed
US-20220338769-A1 METHODS AND APPARATUS FOR SUBSTANCE DELIVERY IN AN IMPLANTABLE DEVICE MCNAIR INTERESTS LTD. 2022-10-27 US claimed
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12605252-B2 Bone density scan result-matched orthopedic implants and methods of use AURORA SPINE, INC. (US) 2026-04-21 US disclosed
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose ENALARE THERAPEUTICS INC. (US) 2026-02-10 US disclosed
US-20250375421-A1 METHODS OF USING DMT SHULMAN WILLIAM (US) 2025-12-11 US disclosed
US-12478481-B2 Bone density scan result-matched orthopedic implants and methods of use AURORA SPINE, INC. (US) 2025-11-25 US disclosed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP disclosed
US-12396981-B2 Methods of using DMT SHULMAN WILLIAM (US) 2025-08-26 US disclosed
US-20250262218-A1 COMPOSITIONS, FORMULATIONS AND METHODS FOR STIMULATING RESPIRATION Auros Pharma LLC 2025-08-21 US disclosed
CN-120033335-A High-entropy flame-retardant electrolyte and preparation method and application thereof 湖北航天化学技术研究所 2025-05-23 CN disclosed
WO-2008063548-A2 5, 6, OR 7-SUBSTITUTED-S- (HETERO)ARYLISOQUINOLINAMINE DERIVATIVES AS ANTITUMOR AGENTS REXAHN PHARMACEUTICALS, INC. (US) 2008-05-29 WO disclosed
US-7297821-B2 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-11-20 US disclosed
EP-1813596-A1 PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE National University Corporation Hokkaido University (JP) 2007-08-01 EP disclosed
US-20060089513-A1 Fluorine compound and fluorinating agent comprising the compound HIDAKA TOSHIO 2006-04-27 US disclosed
US-7019173-B2 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-03-28 US disclosed
US-20040176361-A1 Fused heterocyclic compound and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2004-09-09 US disclosed
EP-1422216-A1 FLUORINE COMPOUND AND FLUORINATING AGENT COMPRISING THE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-05-26 EP disclosed
US-20040073065-A1 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-04-15 US disclosed
EP-1396488-A1 FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2004-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose OPRK1, OPRD1, OPRM1 HPGD 1608/4885SMN1; SMN2 1319/4885MEN1 4885/4885
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ADRA2B, ADRB1, ADRB2 HPGD 1974/4885SMN1; SMN2 1428/4885MEN1 4858/4885
US-12605252-B2 Bone density scan result-matched orthopedic implants and methods of use SOST, BMP2, COL2A1 HPGD 4131/4885SMN1; SMN2 1076/4885MEN1 1522/4885
US-12396981-B2 Methods of using DMT PNMT, HTR6, HTR1A HPGD 2674/4885SMN1; SMN2 370/4885MEN1 1347/4885
US-20250375421-A1 METHODS OF USING DMT PNMT, HTR6, HTR1A HPGD 2674/4885SMN1; SMN2 370/4885MEN1 1347/4885
US-20040176361-A1 Fused heterocyclic compound and medicinal use thereof PARP11, PARP1, CD38 HPGD 77/4885SMN1; SMN2 1795/4885MEN1 1853/4885
US-20060089513-A1 Fluorine compound and fluorinating agent comprising the compound AFF1, AFF2, RER1 HPGD 4000/4885SMN1; SMN2 2281/4885MEN1 611/4885
US-20040073065-A1 Fluorine compound and fluorinating agent comprising the compound AFF1, RER1, AFF2 HPGD 4060/4885SMN1; SMN2 2298/4885MEN1 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.