Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456832 | 0.83 | GRM1 (0.56) | GPR119NAMPTRORCGRM5 | |
| SCHEMBL20139227 | 0.82 | GPR119 (0.53) | GPR119GRM5 | |
| SCHEMBL652792 | 0.80 | GRM5 (0.53) | GPR119NAMPTALDH1A1MAPTGRM5 | |
| SCHEMBL22919200 | 0.78 | AR (0.54) | GPR119IRAK4 | |
| SCHEMBL23123370 | 0.77 | SCN9A (0.43) | GPR119SCN9ANAMPTUSP30RORC | |
| SCHEMBL20139986 | 0.77 | GPR119 (0.46) | GPR119GRM5 | |
| SCHEMBL29795605 | 0.77 | SCN9A (0.43) | GPR119SCN9ANAMPTUSP30RORC | |
| SCHEMBL29795606 | 0.77 | SCN9A (0.43) | GPR119SCN9ANAMPTUSP30RORC | |
| SCHEMBL31432988 | 0.77 | CYP11B2 (0.52) | GPR119MEN1ALDH1A1KMT2AGRM5 | |
| SCHEMBL31432814 | 0.76 | CYP11B2 (0.53) | GPR119GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |