Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140774 | 0.89 | GSK3B (0.38) | HPGDALDH1A1MAPTPLATDYRK1A | |
| SCHEMBL110825 | 0.76 | MGLL (0.42) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14962437 | 0.69 | MGLL (0.41) | ALDH1A1LMNAMAPTDYRK1AGSK3B | |
| SCHEMBL26125901 | 0.69 | PDCD1 (0.38) | HPGDLMNADYRK1AGSK3B | |
| SCHEMBL3434128 | 0.67 | RAB9A (0.48) | HPGDALDH1A1MAPTTP53MEN1 | |
| SCHEMBL929672 | 0.67 | PDCD1 (0.43) | HPGDALDH1A1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL16741194 | 0.66 | PDCD1 (0.43) | HPGDALDH1A1MAPTTP53MEN1 | |
| Hydrochloric Acid SCHEMBL2753179 | 0.66 | PDCD1 (0.43) | HPGDALDH1A1MAPTTP53MEN1 | |
| SCHEMBL2753115 | 0.65 | KDM5B (0.38) | HPGDALDH1A1L3MBTL1MAPTTP53 | |
| Hypochlorous Acid SCHEMBL3087241 | 0.65 | SMO (0.43) | HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |