Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157210 | 0.84 | KDM4E (0.43) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20157036 | 0.84 | HTT (0.43) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20157027 | 0.81 | HTT (0.38) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20157250 | 0.79 | GRIN2B (0.32) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL20157337 | 0.75 | FAAH (0.36) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20156905 | 0.73 | HTT (0.42) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20156901 | 0.71 | HTT (0.41) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20157328 | 0.71 | HTT (0.40) | FAAHALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20157073 | 0.70 | MC4R (0.37) | FAAHALDH1A1HTTKMT2AHRH3 | |
| SCHEMBL20157029 | 0.70 | ALDH1A1 (0.40) | FAAHALDH1A1KDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |