Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156907 | 0.87 | HTT (0.38) | FAAHHTTHRH3ALDH1A1LMNA | |
| SCHEMBL20157535 | 0.86 | HTT (0.36) | FAAHHTTHRH3GPR183PDCD1 | |
| SCHEMBL20156898 | 0.85 | HTT (0.36) | FAAHHTTHRH3ALDH1A1LMNA | |
| SCHEMBL20157301 | 0.84 | HTT (0.35) | FAAHHTTHRH3GPR183ALDH1A1 | |
| SCHEMBL20157061 | 0.83 | HTT (0.35) | FAAHHTTHRH3ALDH1A1KDM4E | |
| SCHEMBL20157031 | 0.81 | HTT (0.35) | FAAHHTTHRH3GPR183L3MBTL1 | |
| SCHEMBL20157073 | 0.81 | MC4R (0.37) | FAAHHTTHRH3GPR183PDCD1 | |
| SCHEMBL20156900 | 0.81 | HTT (0.34) | FAAHHTTHRH3ALDH1A1LMNA | |
| SCHEMBL20157531 | 0.81 | FAAH (0.39) | FAAHHTTHRH3L3MBTL1ALDH1A1 | |
| SCHEMBL20157293 | 0.80 | HTT (0.36) | FAAHHTTHRH3GPR183ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |