Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030752 | 0.84 | LMNA (0.67) | DRD2DRD4KDM4EALDH1A1NPSR1 | |
| SCHEMBL8131885 | 0.84 | ATM (0.67) | DRD2DRD4ALDH1A1ATMHTR7 | |
| SCHEMBL6030972 | 0.83 | ATM (0.62) | DRD2DRD4KDM4EALDH1A1ATM | |
| SCHEMBL8392161 | 0.82 | DRD2 (0.56) | DRD2DRD4KDM4EALDH1A1NPSR1 | |
| SCHEMBL18177896 | 0.82 | ATM (0.64) | DRD2DRD4KDM4EALDH1A1NPSR1 | |
| SCHEMBL11550567 | 0.82 | ATM (0.61) | DRD2DRD4KDM4EALDH1A1NPSR1 | |
| SCHEMBL18171326 | 0.82 | MAPK1 (0.70) | DRD2DRD4KDM4EATMHTR7 | |
| SCHEMBL15938505 | 0.81 | DRD4 (0.70) | DRD2DRD4ATMHTR7 | |
| SCHEMBL16281870 | 0.81 | HTR7 (0.56) | DRD2DRD4KDM4EALDH1A1NPSR1 | |
| SCHEMBL3436468 | 0.79 | ATM (0.57) | DRD2DRD4KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |