Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157082 | 0.92 | MYC (0.54) | MYCMEN1KMT2AHTR7KDM4E | |
| SCHEMBL20156914 | 0.91 | MYC (0.46) | MYCMEN1KMT2AHTR7KDM4E | |
| SCHEMBL20157034 | 0.89 | NPC1 (0.42) | MYCMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20156911 | 0.86 | KDM4E (0.55) | MYCMEN1KMT2AKDM4ECYP2C9 | |
| SCHEMBL20157349 | 0.85 | NPC1 (0.41) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL20157273 | 0.83 | MEN1 (0.47) | MYCMEN1KMT2AHTR7KDM4E | |
| SCHEMBL20157353 | 0.83 | MEN1 (0.47) | MYCMEN1KMT2AHTR7KDM4E | |
| SCHEMBL20157303 | 0.83 | MTOR (0.42) | MYCMEN1KMT2AKDM4ECYP2C9 | |
| SCHEMBL20157035 | 0.82 | NPC1 (0.46) | MYCMEN1KMT2AHTR7KDM4E | |
| SCHEMBL20140200 | 0.81 | MTOR (0.59) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |