Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157078 | 0.86 | MYC (0.47) | KDM4EALDH1A1NPSR1ATMHTT | |
| SCHEMBL12189576 | 0.81 | HTT (0.60) | KDM4EALDH1A1NPSR1HTTLMNA | |
| SCHEMBL20140044 | 0.81 | MTOR (0.54) | KDM4EALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL20157212 | 0.80 | GBA1 (0.51) | KDM4EALDH1A1NPSR1ATMDRD2 | |
| SCHEMBL20157290 | 0.79 | MTOR (0.50) | KDM4EALDH1A1NPSR1ATMDRD2 | |
| SCHEMBL20156914 | 0.77 | MYC (0.46) | KDM4EALDH1A1NPSR1ATMHTT | |
| SCHEMBL20156931 | 0.77 | MTOR (0.51) | KDM4EALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL20157082 | 0.76 | MYC (0.54) | KDM4EALDH1A1NPSR1ATMHTT | |
| SCHEMBL20157034 | 0.76 | NPC1 (0.42) | KDM4EALDH1A1NPSR1SMN1; SMN2MYC | |
| SCHEMBL20157076 | 0.74 | DRD2 (0.62) | KDM4EALDH1A1NPSR1ATMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |