Sugi Predict

Sugi Predict / Compounds / SCHEMBL2015708

SCHEMBL2015708

SCHEMBL2015708

c1ccc(CNC2=NCCS2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ POLB P06746 1/20 0.56
▸ GLA P06280 1/20 0.51
▸ MMP3 P08254 1/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ LMNA P02545 2/20 0.49
▸ TAAR1 Q96RJ0 1/20 0.49
▸ NPC1 O15118 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ MAPK1 P28482 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ ATM Q13315 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4211382 0.98 ALDH1A1 (0.56) ALDH1A1NPSR1POLBGLAMMP3
SCHEMBL11344295 0.83 NPC1 (0.51) ALDH1A1NPSR1POLBSMN1; SMN2LMNA
SCHEMBL2017733 0.83 ALDH1A1 (0.82) ALDH1A1NPSR1POLBMMP3SMN1; SMN2
SCHEMBL11343118 0.83 TSHR (0.48) ALDH1A1NPSR1POLBSMN1; SMN2NPC1
SCHEMBL11350430 0.83 NPC1 (0.51) ALDH1A1NPSR1POLBSMN1; SMN2NPC1
SCHEMBL3708273 0.82 HSD17B10 (0.55) ALDH1A1NPSR1POLBHSD17B10L3MBTL1
SCHEMBL11513289 0.82 KMT2A (0.48) ALDH1A1NPSR1POLBGLASMN1; SMN2
SCHEMBL1179183 0.81 KMT2A (0.47) ALDH1A1NPSR1LMNAATML3MBTL1
SCHEMBL1178466 0.81 MAPK1 (0.45) ALDH1A1NPSR1POLBSMN1; SMN2LMNA
SCHEMBL11349824 0.78 SMN1; SMN2 (0.48) ALDH1A1NPSR1POLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103215108-B Internal combustion engine fuel-economizing lubricant oil composite 雪佛龙日本有限公司 2017-03-01 — — CN disclosed
CN-101987986-B Friction modifier and transmission oil CHEVRON JAPAN LTD 2014-07-09 — — CN disclosed
CN-103305318-A Lubricating oil composition for automibile engine lubrication CHEVRON JAPAN LTD 2013-09-18 — — CN disclosed
CN-103215108-A Fuel economical lubricating oil compositions for internal combustion engines CHEVRON JAPAN LTD 2013-07-24 — — CN disclosed
EP-2176232-B1 1-(AZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2013-06-19 — — EP disclosed
CN-101379171-B Lubricant base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for transmission device NIPPON OIL CORP 2012-12-19 — — CN disclosed
CN-101454431-B Lubricating oil base oil, preparation method thereof and lubricating oil composition NIPPON OIL CORP 2012-10-17 — — CN disclosed
US-8221775-B2 Pyrrolin-2-ylamino compounds for combating animal pests BASF SE (DE) 2012-07-17 — — US disclosed
US-8211924-B2 1-(azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2012-07-03 — — US disclosed
US-8193118-B2 Insecticidal substituted benzylamino heterocyclic and heteroaryl derivatives FMC CORPORATION (US) 2012-06-05 — — US disclosed
US-20100280078-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2010-11-04 — — US disclosed
EP-2176232-A1 1-(AZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-04-21 — — EP disclosed
WO-2010029069-A1 PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-03-18 — — WO disclosed
CN-101454431-A Lubricating oil base oil, preparation method thereof and lubricating oil composition NIPPON OIL CORP (JP) 2009-06-10 — — CN disclosed
CN-101379171-A Lubricant base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for transmission device NIPPON OIL CORP (JP) 2009-03-04 — — CN disclosed
US-20090036306-A1 Insecticidal Substituted Benzylamino Heterocyclic and Heteroaryl Derivatives BAYER CROPSCIENCE AG (DE) 2009-02-05 — — US disclosed
US-20090036306-A1 Insecticidal Substituted Benzylamino Heterocyclic and Heteroaryl Derivatives BAYER CROPSCIENCE AG (DE) 2009-02-05 — — US disclosed
WO-2009004032-A1 1-(AZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2009-01-08 — — WO disclosed
EP-1885180-A2 INSECTICIDAL SUBSTITUTED BENZYLAMINO HETEROCYCLIC AND HETEROARYL DERIVATIVES Bayer CropScience AG (DE) 2008-02-13 — — EP disclosed
WO-2006127426-A2 INSECTICIDAL SUBSTITUTED BENZYLAMINO HETEROCYCLIC AND HETEROARYL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036306-A1 Insecticidal Substituted Benzylamino Heterocyclic and Heteroaryl Derivatives DDT, AADAC, CYP4B1 ALDH1A1 500/4885NPSR1 2319/4885POLB 4631/4885
US-20100280078-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests NR0B1, NR0B2, NR2C2 ALDH1A1 752/4885NPSR1 76/4885POLB 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.