Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015708 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NPSR1TSHRL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL4211382 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPSR1TSHRL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL8573312 | 0.75 | POLB (0.58) | ALDH1A1NPSR1TSHRPOLBNPY1R | |
| SCHEMBL13956095 | 0.71 | ALDH1A1 (0.52) | ALDH1A1NPSR1L3MBTL1EPHX2SMN1; SMN2 | |
| SCHEMBL4217069 | 0.70 | ADRA2A (0.52) | ALDH1A1NPSR1TSHRL3MBTL1ATM | |
| SCHEMBL3708273 | 0.70 | HSD17B10 (0.55) | ALDH1A1NPSR1L3MBTL1POLBKDM4E | |
| SCHEMBL11349824 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1NPSR1TSHRL3MBTL1ATM | |
| SCHEMBL9658772 | 0.68 | POLB (0.70) | ALDH1A1NPSR1POLBSMN1; SMN2KDM4E | |
| SCHEMBL11132646 | 0.67 | CXCR4 (0.56) | ALDH1A1NPSR1TSHRL3MBTL1EPHX2 | |
| SCHEMBL11344295 | 0.67 | NPC1 (0.51) | ALDH1A1NPSR1TSHRL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221775-B2 | Pyrrolin-2-ylamino compounds for combating animal pests | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| EP-2346822-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | BASF SE | 2011-06-30 | — | — | US | disclosed |
| WO-2010029069-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | RXFP3, CBR3, ATL3 | ALDH1A1 2824/4885NPSR1 285/4885TSHR 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.