Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30721187 | 0.84 | HCAR3 (0.53) | HCAR3MKNK1MKNK2GPR55KIT | |
| SCHEMBL4748840 | 0.84 | HCAR3 (0.53) | HCAR3MKNK1MKNK2GPR55KIT | |
| Hydrochloric Acid SCHEMBL3718104 | 0.82 | ADRA2A (0.53) | HCAR3MKNK1MKNK2GPR55KIT | |
| Hydrochloric Acid SCHEMBL3938816 | 0.82 | ADRA2A (0.53) | HCAR3MKNK1MKNK2GPR55KIT | |
| SCHEMBL20156855 | 0.81 | FERMT2 (0.44) | HCAR3TDO2MKNK1MKNK2GPR55 | |
| SCHEMBL10293613 | 0.78 | HCAR3 (0.57) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL18307133 | 0.77 | HCAR3 (0.56) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13947117 | 0.77 | HCAR3 (0.56) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12963036 | 0.77 | HCAR3 (0.56) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12327198 | 0.77 | HCAR3 (0.56) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |