Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157086 | 0.81 | HCAR3 (0.56) | TDO2MKNK1MKNK2GPR55IDH1 | |
| SCHEMBL8188968 | 0.80 | AURKA (0.51) | CCNT1GPR55LCK | |
| SCHEMBL2028729 | 0.78 | HRH3 (0.42) | FERMT2CHEK1HCAR3PRKD3EGFR | |
| SCHEMBL18768716 | 0.77 | DEGS1 (0.41) | CHEK1HCAR3 | |
| SCHEMBL1060108 | 0.77 | NPC1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL5694428 | 0.77 | HRH3 (0.41) | FERMT2CHEK1HCAR3PRKD3EGFR | |
| SCHEMBL13103613 | 0.77 | RAB9A (0.47) | SYKHCAR3PRKD3EGFRPRKCG | |
| SCHEMBL5206693 | 0.77 | MAOB (0.51) | FERMT2IDH1 | |
| SCHEMBL5093662 | 0.77 | RAB9A (0.54) | — | |
| SCHEMBL24661308 | 0.76 | TDO2 (0.41) | TDO2MKNK1MKNK2GPR55IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |