Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157133 | 0.88 | MTOR (0.39) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL20157131 | 0.88 | CFTR (0.40) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL20142330 | 0.87 | HTR6 (0.45) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20141590 | 0.86 | HTR6 (0.46) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL20140911 | 0.77 | HTR6 (0.44) | MTORRPTORMLST8DRD4DRD2 | |
| SCHEMBL20141270 | 0.77 | HTR6 (0.44) | MTORRPTORMLST8DRD4DRD2 | |
| SCHEMBL20140762 | 0.76 | HTR6 (0.47) | ALDH1A1LMNASMN1; SMN2MTORRPTOR | |
| SCHEMBL20157174 | 0.75 | POLB (0.39) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL20157132 | 0.71 | TACR3 (0.47) | SMN1; SMN2MTORRPTORMLST8L3MBTL1 | |
| SCHEMBL20139916 | 0.69 | MTOR (0.54) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |