Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140911 | 0.88 | HTR6 (0.44) | HTR6KDM1ADRD2HTR1AHTR2A | |
| SCHEMBL20141270 | 0.88 | HTR6 (0.44) | HTR6KDM1ADRD2HTR1AHTR2A | |
| SCHEMBL20140762 | 0.87 | HTR6 (0.47) | HTR6KDM1ADRD2HTR2AALDH1A1 | |
| SCHEMBL20157134 | 0.86 | ALDH1A1 (0.40) | HTR6KDM1ADRD2MEN1ALDH1A1 | |
| SCHEMBL20157133 | 0.77 | MTOR (0.39) | HTR6KDM1ADRD2MEN1ALDH1A1 | |
| SCHEMBL20157131 | 0.77 | CFTR (0.40) | HTR6KDM1ADRD2MEN1ALDH1A1 | |
| SCHEMBL20157106 | 0.76 | HTR6 (0.46) | HTR6KDM1ADRD2HTR1AHTR2A | |
| SCHEMBL20142330 | 0.76 | HTR6 (0.45) | HTR6DRD2HTR2AMEN1ALDH1A1 | |
| SCHEMBL20140817 | 0.74 | AKR1C3 (0.50) | HTR6MEN1HTTKMT2AALOX5 | |
| SCHEMBL20140396 | 0.72 | HTR6 (0.45) | HTR6KDM1ADRD2HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |