Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157531 | 0.92 | FAAH (0.39) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157226 | 0.91 | ALDH1A1 (0.34) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157031 | 0.89 | HTT (0.35) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20156907 | 0.87 | HTT (0.38) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20156903 | 0.85 | HTT (0.35) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157246 | 0.85 | CYP1A2 (0.30) | POLB | |
| SCHEMBL20157028 | 0.85 | FAAH (0.35) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157318 | 0.84 | ALDH1A1 (0.35) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157294 | 0.83 | MC4R (0.36) | HTTFAAHMC4RMC5RLMNA | |
| SCHEMBL20157073 | 0.83 | MC4R (0.37) | HTTFAAHMC4RMC5RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |