Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156898 | 0.90 | HTT (0.36) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157061 | 0.88 | HTT (0.35) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157293 | 0.87 | HTT (0.36) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157337 | 0.87 | FAAH (0.36) | HTTFAAHHRH3LMNAALDH1A1 | |
| SCHEMBL20157535 | 0.87 | HTT (0.36) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20156900 | 0.85 | HTT (0.34) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157301 | 0.85 | HTT (0.35) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157226 | 0.78 | ALDH1A1 (0.34) | HTTFAAHLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20156910 | 0.78 | HTT (0.34) | HTTFAAHHRH3LMNASMN1; SMN2 | |
| SCHEMBL20157315 | 0.78 | CYP1A2 (0.32) | SMN1; SMN2ALDH1A1PHGDHPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |