Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 4/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767621 | 0.72 | AAK1 (0.33) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL17282958 | 0.71 | KDM4E (0.35) | PCSK9DGAT1FPR2 | |
| SCHEMBL88124 | 0.71 | CCNE2 (0.38) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL20157340 | 0.70 | CCNE2 (0.42) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL18681721 | 0.70 | FPR2 (0.37) | PCSK9DGAT1AAK1FPR2 | |
| SCHEMBL24509637 | 0.69 | CYP17A1 (0.39) | PCSK9DGAT1BRD4FPR2 | |
| SCHEMBL6749699 | 0.69 | KDM4E (0.44) | PCSK9DGAT1BRD4FPR2 | |
| SCHEMBL6521889 | 0.69 | BRAF (0.38) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6521886 | 0.69 | BRAF (0.38) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL14738392 | 0.68 | DGAT1 (0.42) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |