Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157308 | 0.91 | CHRM4 (0.44) | CHRM4TRPV1HCRTR2MALT1CHRM2 | |
| SCHEMBL20157345 | 0.88 | CHRM4 (0.41) | CHRM4GRM1TRPV1HCRTR2MALT1 | |
| SCHEMBL20157350 | 0.88 | CHRM4 (0.41) | CHRM4GRM1TRPV1HCRTR2MALT1 | |
| SCHEMBL20156810 | 0.87 | MTOR (0.47) | CHRM4GRM1TRPV1HCRTR2CHRM2 | |
| SCHEMBL20157309 | 0.87 | MTOR (0.47) | CHRM4GRM1TRPV1HCRTR2CHRM2 | |
| SCHEMBL20140812 | 0.87 | ALDH1A1 (0.56) | CHRM4ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL20157004 | 0.83 | CHRM4 (0.47) | CHRM4GRM1ALDH1A1CHRM2MEN1 | |
| SCHEMBL20157005 | 0.83 | CHRM4 (0.47) | CHRM4GRM1ALDH1A1CHRM2MEN1 | |
| SCHEMBL20141840 | 0.80 | GRM1 (0.49) | CHRM4GRM1ALDH1A1HSD11B1CHRM2 | |
| SCHEMBL20140106 | 0.80 | GRM1 (0.47) | CHRM4GRM1ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |