Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157436 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL20141633 | 0.87 | DRD4 (0.46) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL20139931 | 0.85 | LMNA (0.43) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL20157437 | 0.83 | MTOR (0.45) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL20156839 | 0.80 | RET (0.37) | ALDH1A1LMNADRD4RET | |
| SCHEMBL20156841 | 0.76 | DRD4 (0.51) | ALDH1A1LMNADRD4 | |
| SCHEMBL20157090 | 0.74 | DRD4 (0.47) | ALDH1A1LMNADRD4 | |
| SCHEMBL8415328 | 0.74 | DRD4 (0.46) | ALDH1A1GAADRD4L3MBTL1 | |
| SCHEMBL20156840 | 0.72 | RET (0.39) | ALDH1A1LMNADRD4RET | |
| SCHEMBL20156796 | 0.72 | MTOR (0.47) | ALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |