Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139931 | 0.90 | LMNA (0.43) | RAB9ALMNANPC1ALDH1A1KMT2A | |
| SCHEMBL20156796 | 0.89 | MTOR (0.47) | MTORRPTORMLST8ALDH1A1THRB | |
| SCHEMBL20140052 | 0.88 | MTOR (0.45) | MTORRPTORMLST8RAB9ALMNA | |
| SCHEMBL20141633 | 0.86 | DRD4 (0.46) | RAB9ALMNANPC1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL20140050 | 0.84 | MTOR (0.46) | MTORRPTORMLST8ALDH1A1THRB | |
| SCHEMBL20156795 | 0.84 | MTOR (0.49) | MTORRPTORMLST8ALDH1A1THRB | |
| SCHEMBL20157436 | 0.84 | ALDH1A1 (0.42) | RAB9ALMNANPC1ALDH1A1KMT2A | |
| SCHEMBL20157438 | 0.83 | ALDH1A1 (0.41) | RAB9ALMNANPC1ALDH1A1KMT2A | |
| SCHEMBL20142054 | 0.80 | MTOR (0.45) | MTORRPTORMLST8ALDH1A1THRB | |
| SCHEMBL20140200 | 0.79 | MTOR (0.59) | MTORRPTORMLST8ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |