Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986411 | 0.82 | ALOX15 (0.55) | MAPTKDM4EALDH1A1DNM1CYP2C9 | |
| SCHEMBL12600218 | 0.81 | TP53 (0.44) | MAPTKDM4EALDH1A1DNM1HTT | |
| SCHEMBL1989064 | 0.78 | DNM1 (0.49) | DNM1 | |
| SCHEMBL10820432 | 0.76 | CDK1 (0.74) | KDM4EALDH1A1HTTCDK1MALT1 | |
| SCHEMBL1986412 | 0.73 | GAA (0.57) | KDM4EDNM1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL10123981 | 0.73 | MTNR1A (0.60) | ALDH1A1CYP2C9CYP2C19ALOX15 | |
| SCHEMBL1384166 | 0.73 | HPGD (0.49) | MAPTKDM4EALDH1A1HTTCDK1 | |
| SCHEMBL1384164 | 0.73 | HPGD (0.49) | MAPTKDM4EALDH1A1HTTCDK1 | |
| SCHEMBL6573383 | 0.72 | CDK1 (0.67) | KDM4EALDH1A1CDK1MALT1 | |
| SCHEMBL5019657 | 0.71 | SLC6A4 (0.51) | ALDH1A1CYP2C9CYP2C19ACKR3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026150-B1 | (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-6573297-B2 | Applying an effective amount of (2-substituted oxyphenyl)alkanamide derivatives to the skin of a mammal for promoting hair growth | SHISEIDO CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20020052498-A1 | (2-substituted oxyphenyl)alkanamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2002-05-02 | — | — | US | disclosed |
| US-6339154-B1 | THERAPY OF HAIR LOSS IN MAMMALS AND, IN PARTICULAR, IN HUMAN | SHISEIDO CO, LTD. (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-1026150-A1 | (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052498-A1 | (2-substituted oxyphenyl)alkanamide derivative, hair growth promoter and external composition for skin using the same | NR2E1, NCOR2, DECR2 | MAPT 4560/4885KDM4E 156/4885ALDH1A1 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.