Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15297554 | 0.78 | NR1H2 (0.40) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL26637275 | 0.77 | GPR119 (0.39) | EPHX2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15297743 | 0.77 | GPR119 (0.43) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL22999775 | 0.75 | NR1H2 (0.39) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL31247881 | 0.75 | EHMT2 (0.39) | EPHX2EHMT2ALDH1A1TSHRMEN1 | |
| SCHEMBL22317711 | 0.74 | NR1H2 (0.40) | EPHX2EHMT2ALDH1A1TSHRMEN1 | |
| SCHEMBL22999796 | 0.74 | EPHX1 (0.42) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL6488909 | 0.72 | NFKB1 (0.39) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL26092527 | 0.72 | NR1H2 (0.35) | EPHX2EHMT2ALDH1A1TSHRMEN1 | |
| SCHEMBL30487540 | 0.72 | STS (0.35) | CETPEHMT2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089355-A1 | CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |