Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096857 | 0.84 | TUBB1 (0.59) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL30882817 | 0.83 | TRPA1 (0.66) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL29130913 | 0.82 | TUBB1 (0.47) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL29778007 | 0.81 | TRPA1 (0.68) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL33786 | 0.81 | TRPA1 (0.68) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL23714702 | 0.80 | TUBB1 (0.49) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL1159623 | 0.80 | ALDH1A1 (0.68) | TUBB1ALDH1A1TSHRMAPTTRIM24 | |
| SCHEMBL16957857 | 0.79 | ALDH1A1 (0.44) | TRPA1ALDH1A1TSHR | |
| Methoxymethane SCHEMBL28668338 | 0.79 | TRPA1 (0.66) | TRPA1TUBB1TUBB4ATUBBTUBA3C | |
| Ethylene SCHEMBL28209809 | 0.79 | TRPA1 (0.66) | TRPA1TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597733-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2023-03-07 | — | — | US | disclosed |
| WO-2021078120-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-04-29 | — | — | WO | disclosed |
| US-20210115065-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-04-22 | — | — | US | disclosed |
| WO-2018086605-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597733-B2 | Compounds and compositions for the treatment of parasitic diseases | ABCB11, SQLE, FURIN | TRPA1 2228/4885TUBB1 1192/4885TUBB4A 1402/4885 |
| US-20210115065-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | ABCB11, SQLE, FURIN | TRPA1 2228/4885TUBB1 1192/4885TUBB4A 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.