Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362446 | 1.00 | BRD4 (0.36) | BRD4ACHETAS1R3TAS1R1 | |
| SCHEMBL20157434 | 0.79 | BRD4 (0.33) | BRD4 | |
| SCHEMBL21362138 | 0.79 | BRD4 (0.38) | BRD4ACHETAS1R3TAS1R1 | |
| SCHEMBL21362238 | 0.78 | BRD4 (0.37) | BRD4ACHETAS1R3TAS1R1 | |
| SCHEMBL21362057 | 0.78 | MAPK14 (0.32) | BRD4 | |
| SCHEMBL21362147 | 0.76 | BRD4 (0.31) | BRD4 | |
| SCHEMBL21352136 | 0.76 | BRD4 (0.38) | BRD4ACHETAS1R3TAS1R1 | |
| SCHEMBL21564841 | 0.75 | DRD4 (0.32) | BRD4 | |
| SCHEMBL20157926 | 0.73 | BRD4 (0.37) | BRD4 | |
| SCHEMBL20157431 | 0.73 | THRB (0.34) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086605-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |