SCHEMBL201585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL201401	0.91	MAPT (0.47)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL202936	0.89	CASP3 (0.44)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL201971	0.88	CASP3 (0.59)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL2319016	0.87	MAPT (0.49)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL203129	0.85	MAPT (0.53)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL201233	0.84	MAPT (0.57)	MAPTL3MBTL1ALDH1A1LMNAHTT
	SCHEMBL202105	0.83	GSTP1 (0.55)	MAPTL3MBTL1ALDH1A1LMNAHTT
	SCHEMBL202214	0.83	MAPT (0.58)	MAPTL3MBTL1HTTSMN1; SMN2TP53
	SCHEMBL2316477	0.82	CASP3 (0.45)	CASP3SENP8SENP7SENP6MAPT
	SCHEMBL201364	0.82	TSHR (0.55)	CASP3SENP8SENP7SENP6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.