Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26831785 | 0.75 | HRH3 (0.51) | ARHRH3LMNA | |
| SCHEMBL25844914 | 0.72 | AR (0.41) | ARHRH3TP53LMNAKMT2A | |
| SCHEMBL26831781 | 0.71 | AR (0.43) | ARTP53LMNA | |
| SCHEMBL13287985 | 0.68 | AR (0.35) | AR | |
| SCHEMBL21301425 | 0.68 | CYP1A2 (0.50) | LMNA | |
| SCHEMBL21727617 | 0.64 | — | — | |
| SCHEMBL3674837 | 0.64 | TDP1 (0.46) | ARMEN1KMT2A | |
| SCHEMBL4476856 | 0.64 | AR (0.47) | ARHRH3TP53LMNAMEN1 | |
| SCHEMBL2796432 | 0.64 | POLB (0.49) | ARHRH3TP53LMNAMEN1 | |
| SCHEMBL25060325 | 0.63 | ALDH1A1 (0.37) | TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |