Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663195 | 0.83 | HRH3 (0.50) | HRH3ARHTTHPGDSMN1; SMN2 | |
| SCHEMBL27316791 | 0.77 | L3MBTL1 (0.45) | HRH3ARHPGDNPC1RAB9A | |
| SCHEMBL20581159 | 0.77 | TP53 (0.50) | HRH3ARRAB9ALMNA | |
| SCHEMBL20158924 | 0.75 | AR (0.44) | HRH3ARLMNA | |
| SCHEMBL26831781 | 0.74 | AR (0.43) | ARRAB9ALMNAALDH1A1 | |
| SCHEMBL14930399 | 0.73 | SMN1; SMN2 (0.51) | HTTHPGDNPC1RAB9ALMNA | |
| SCHEMBL6465429 | 0.73 | HPGD (0.68) | HTTHPGDLMNASMN1; SMN2KDM4E | |
| SCHEMBL5655224 | 0.72 | ALDH1A1 (0.69) | HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27249721 | 0.70 | NPC1 (0.47) | HRH3HTTHPGDNPC1RAB9A | |
| SCHEMBL17473523 | 0.70 | SMN1; SMN2 (0.48) | HTTHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023223055-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2023-11-23 | — | — | WO | disclosed |