Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25848798 | 0.73 | NOTUM (0.42) | LMNA | |
| SCHEMBL20158924 | 0.72 | AR (0.44) | ARKMT2ATP53LMNAHRH3 | |
| SCHEMBL25851541 | 0.71 | HPGD (0.37) | KMT2A | |
| SCHEMBL25853202 | 0.71 | KDM4E (0.39) | KMT2ALMNA | |
| SCHEMBL26831785 | 0.69 | HRH3 (0.51) | ARLMNAHRH3 | |
| SCHEMBL25848676 | 0.68 | NAMPT (0.33) | HDAC6HDAC8 | |
| SCHEMBL25842594 | 0.66 | CGAS (0.39) | KMT2A | |
| SCHEMBL26831781 | 0.66 | AR (0.43) | ARTP53LMNA | |
| SCHEMBL25851587 | 0.66 | ALDH1A1 (0.38) | KMT2ALMNA | |
| SCHEMBL25853945 | 0.65 | GRM5 (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |