Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.52 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159039 | 0.86 | MTOR (0.60) | MTORRPTORMLST8DRD2CHRM4 | |
| Hydrochloric Acid SCHEMBL20140946 | 0.85 | MTOR (0.59) | MTORRPTORMLST8DRD2CHRM4 | |
| Hydrochloric Acid SCHEMBL20140947 | 0.85 | MTOR (0.59) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20159042 | 0.82 | DRD2 (0.42) | DRD2CHRM4LMNATP53MAPT | |
| SCHEMBL20141650 | 0.77 | MTOR (0.71) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20141653 | 0.77 | MTOR (0.71) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20159012 | 0.77 | MTOR (0.72) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20159113 | 0.75 | MTOR (0.73) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20141139 | 0.75 | MTOR (0.72) | MTORRPTORMLST8DRD2CHRM4 | |
| SCHEMBL20141137 | 0.75 | MTOR (0.72) | MTORRPTORMLST8DRD2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |