Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705715 | 0.86 | AR (0.53) | NR1H2NR1H3SUV39H2MAP4K4 | |
| SCHEMBL705714 | 0.86 | AR (0.53) | NR1H2NR1H3SUV39H2MAP4K4 | |
| SCHEMBL30208177 | 0.84 | NR1H2 (0.55) | NR1H2NR1H3FAAHSUV39H2 | |
| SCHEMBL20139232 | 0.84 | NR1H2 (0.55) | NR1H2NR1H3FAAHSUV39H2 | |
| SCHEMBL20141060 | 0.84 | NR1H2 (0.55) | NR1H2NR1H3FAAHSUV39H2MAP4K4 | |
| SCHEMBL15819221 | 0.82 | FAAH (0.56) | NR1H2NR1H3FAAHMAP4K4 | |
| SCHEMBL20139199 | 0.82 | FAAH (0.56) | NR1H2NR1H3FAAHMAP4K4 | |
| SCHEMBL16933542 | 0.82 | NR1H2 (0.57) | NR1H2NR1H3FAAHSUV39H2MAP4K4 | |
| SCHEMBL688078 | 0.82 | GPR119 (0.56) | NOTUMFAAH | |
| SCHEMBL29767485 | 0.81 | CHRM4 (0.53) | CHRM2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |