Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159274 | 0.85 | HTR2A (0.37) | HTR2ASLC6A4KCNH2MPLF2RL3 | |
| SCHEMBL20159982 | 0.79 | SCN4A (0.38) | KCNH2KDM4EALDH1A1MAPTKDR | |
| SCHEMBL20159730 | 0.77 | MAP4K4 (0.39) | KDM4EALDH1A1MAPTHPGDKDR | |
| SCHEMBL20159650 | 0.74 | PSEN1 (0.51) | HTR2AMGLLABL1SRC | |
| SCHEMBL23492803 | 0.74 | PSEN1 (0.47) | HTR2ASLC6A4KCNH2PI4KB | |
| SCHEMBL20159739 | 0.74 | PSEN1 (0.44) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL23492802 | 0.74 | PSEN1 (0.47) | HTR2ASLC6A4KCNH2PI4KB | |
| SCHEMBL23492800 | 0.74 | PSEN1 (0.47) | HTR2ASLC6A4KCNH2PI4KB | |
| SCHEMBL20159971 | 0.73 | AR (0.33) | CDK8KDRMGLLABL1SRC | |
| SCHEMBL20142944 | 0.73 | AR (0.33) | MAPTCDK8MGLLABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |