Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16061377 | 1.00 | CTSK (0.40) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL571467 | 1.00 | CTSK (0.40) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL22962388 | 0.87 | CTSK (0.37) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL10100401 | 0.85 | CA1 (0.40) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL10776406 | 0.85 | CA1 (0.40) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL12571335 | 0.83 | MAPK10 (0.41) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL15096829 | 0.83 | MAPK10 (0.41) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL1933452 | 0.82 | CTSK (0.39) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL2877516 | 0.82 | CTSK (0.39) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL166623 | 0.81 | CA1 (0.42) | CTSKCA1CA7CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254133-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-12-23 | — | — | WO | disclosed |
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |