Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473610 | 1.00 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL1027840 | 1.00 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL135552 | 0.93 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL28438742 | 0.93 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL1029400 | 0.90 | TSHR (0.44) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL2139803 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Iodide SCHEMBL6657020 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL336735 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL3577655 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Water SCHEMBL3700992 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118382625-A | Pyridine [4,3-d ] pyrimidines as TLR7/8 agonists | 上海维申医药有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-110167560-B | Tetracycline compounds and methods of treatment | 四相制药公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114262301-A | Small molecule antagonist targeting EP4 receptor and application thereof in osteoarthritis and cartilage defect treatment | 华东师范大学 | 2022-04-01 | — | — | CN | disclosed |
| US-11214582-B2 | 4-substituted benzoxaborole compounds and uses thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2022-01-04 | — | — | US | disclosed |
| EP-3560923-B1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20210053996-A1 | 4-Substituted Benzoxaborole Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2021-02-25 | — | — | US | disclosed |
| US-10774096-B2 | 4-substituted benzoxaborole compounds and uses thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-09-15 | — | — | US | disclosed |
| EP-3256479-B1 | 4 -SUBSTITUTED BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-29 | — | — | EP | disclosed |
| EP-3560923-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-3078664-B1 | ANTIPARASITIC DIHYDROAZOLE COMPOSITIONS | MERIAL INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-9376434-B2 | Antiparisitic dihydroazole compounds and compositions comprising same | MERIAL INC. (US) | 2016-06-28 | — | — | US | disclosed |
| EP-2513104-B1 | ANTIPARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL INC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-20150183785-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL, INC. (US) | 2015-07-02 | — | — | US | disclosed |
| US-8980893-B2 | Antiparisitic dihydroazole compounds and compositions comprising same | MERIAL, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2014-10-23 | — | — | US | disclosed |
| US-8618126-B2 | Antiparisitic dihydroazole compounds and compositions comprising same | MERIAL LIMITED (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2513104-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | Merial Limited (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075591-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL, INC. | 2011-06-23 | — | — | US | disclosed |
| WO-2005029552-A2 | SN-C STRUCTURES PREPARED BY PLASMA-ENHANCED CHEMICAL VAPOR DEPOSITION | MIDWEST RESEARCH INSTITUTE (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | DDT, CYP1A1, CYP1A2 | TSHR 3439/4885LMNA 2295/4885THRB 4428/4885 |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | DDT, CYP1A1, CYP1A2 | TSHR 3439/4885LMNA 2295/4885THRB 4428/4885 |
| US-20210053996-A1 | 4-Substituted Benzoxaborole Compounds and Uses Thereof | BRI3BP, CBR3, CYCS | TSHR 2375/4885LMNA 2141/4885THRB 1266/4885 |
| US-11214582-B2 | 4-substituted benzoxaborole compounds and uses thereof | BRI3BP, CBR3, CYCS | TSHR 2375/4885LMNA 2141/4885THRB 1266/4885 |
| US-20150183785-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | DDT, CYP1A1, CYP1A2 | TSHR 3439/4885LMNA 2295/4885THRB 4428/4885 |
| US-10774096-B2 | 4-substituted benzoxaborole compounds and uses thereof | BRD4, BRD3, CBR3 | TSHR 1859/4885LMNA 1742/4885THRB 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.