Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24206569 | 0.82 | DUT (0.32) | DUT | |
| SCHEMBL26968156 | 0.82 | GPR84 (0.35) | GPR84PNMTTAAR1KCNH2DUT | |
| SCHEMBL1895137 | 0.82 | ESRRG (0.37) | TAAR1KCNH2MAPTMAPK1GLA | |
| SCHEMBL29682062 | 0.82 | DUT (0.32) | DUT | |
| SCHEMBL29812483 | 0.82 | GPR84 (0.35) | GPR84PNMTTAAR1KCNH2DUT | |
| SCHEMBL3363843 | 0.78 | GPR84 (0.42) | GPR84KCNH2 | |
| SCHEMBL1245973 | 0.78 | ELOVL1 (0.41) | TAAR1KCNH2DUTIDO1SIGMAR1 | |
| SCHEMBL1246200 | 0.77 | CYP4F2 (0.33) | DUTMAPK1 | |
| SCHEMBL31155534 | 0.77 | DUT (0.31) | DUT | |
| SCHEMBL21356206 | 0.77 | DUT (0.32) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066389-B2 | Process for the manufacturing of medicaments | GENENTECH, INC. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200190061-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2020-06-18 | — | — | US | disclosed |
| US-10611753-B2 | Process for the manufacturing of medicaments | GENENTECH, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180134685-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611753-B2 | Process for the manufacturing of medicaments | ARSA, F8, CYP4A11 | GPR84 3713/4885ANO1 3714/4885PNMT 4771/4885 |
| US-11066389-B2 | Process for the manufacturing of medicaments | ARSA, F8, CYP4A11 | GPR84 3713/4885ANO1 3714/4885PNMT 4771/4885 |
| US-20180134685-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | ARSA, F8, CYP4A11 | GPR84 3713/4885ANO1 3714/4885PNMT 4771/4885 |
| US-20200190061-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | ARSA, F8, CYP4A11 | GPR84 3713/4885ANO1 3714/4885PNMT 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.