Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585566 | 0.78 | NTRK1 (0.55) | KMT2AMEN1LMNANPSR1NTRK1 | |
| SCHEMBL20132409 | 0.75 | MAPK1 (0.48) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL20132408 | 0.73 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL992947 | 0.72 | KMT2A (0.47) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL9391467 | 0.69 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL17681355 | 0.67 | HPGD (0.56) | SLC22A12KMT2AMEN1POLBATM | |
| SCHEMBL14234945 | 0.67 | NPSR1 (0.43) | HDAC1HDAC6SLC22A12NPSR1MAPK10 | |
| SCHEMBL22137313 | 0.67 | NPSR1 (0.43) | HDAC1HDAC6SLC22A12NPSR1MAPK10 | |
| SCHEMBL21946082 | 0.66 | MEN1 (0.42) | KMT2AMEN1ATM | |
| SCHEMBL25501705 | 0.66 | KDM4E (0.46) | KMT2AMEN1POLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089651-A1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | ACETYLON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |