SCHEMBL20132409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20132408	0.82	HDAC3 (0.59)	HDAC3HDAC1HDAC2HDAC6KDM4E
	SCHEMBL20160948	0.75	HDAC3 (0.42)	HDAC3HDAC1HDAC2HDAC6LMNA
	SCHEMBL22031779	0.73	MAPK1 (0.62)	MAPK1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL25501688	0.72	GABRA1 (0.62)	MAPK1GABRA1GABRG2GABRB3GABRA5
	Hydrochloric Acid SCHEMBL22031814	0.71	MAPK1 (0.61)	MAPK1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL29260502	0.71	MAPK1 (0.61)	MAPK1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL5972249	0.71	GABRP (0.45)	MAPK1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL19794412	0.71	MAPK1 (0.56)	MAPK1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL31598929	0.70	MAPK1 (0.59)	MAPK1KDM4EALDH1A1LMNACYP1A2
	SCHEMBL11390294	0.70	MAPK1 (0.59)	MAPK1KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.