Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140433 | 0.83 | L3MBTL1 (0.49) | L3MBTL1PTGDR2ALDH1A1LMNAMAPK1 | |
| SCHEMBL20140277 | 0.80 | ELANE (0.46) | L3MBTL1PTGDR2ALDH1A1LMNAMAPK1 | |
| SCHEMBL21787380 | 0.77 | L3MBTL1 (0.44) | L3MBTL1PTGDR2 | |
| SCHEMBL13562830 | 0.77 | L3MBTL1 (0.67) | L3MBTL1PDE10ATSHRHTTSMN1; SMN2 | |
| SCHEMBL19264342 | 0.76 | L3MBTL1 (0.42) | L3MBTL1USP2CYP17A1CYP1A2 | |
| SCHEMBL20552850 | 0.74 | L3MBTL1 (0.63) | L3MBTL1PDE10AALDH1A1TSHRHTT | |
| SCHEMBL19152217 | 0.73 | L3MBTL1 (0.66) | L3MBTL1 | |
| SCHEMBL25757542 | 0.72 | L3MBTL1 (0.60) | L3MBTL1PTGDR2PDE10AALDH1A1LMNA | |
| SCHEMBL20139756 | 0.70 | L3MBTL1 (0.51) | L3MBTL1PTGDR2 | |
| SCHEMBL20161279 | 0.70 | L3MBTL1 (0.37) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |