Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636626 | 0.88 | L3MBTL1 (0.55) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL12635924 | 0.88 | L3MBTL1 (0.57) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL12635695 | 0.88 | MEN1 (0.66) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL12634827 | 0.85 | HTT (0.57) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL12635728 | 0.85 | L3MBTL1 (0.54) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL12634804 | 0.83 | LMNA (0.66) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL20062853 | 0.83 | L3MBTL1 (0.58) | L3MBTL1HPGDSMN1; SMN2RECQLKMT2A | |
| SCHEMBL28366489 | 0.83 | MAPT (0.70) | L3MBTL1SMN1; SMN2RECQLKMT2AMEN1 | |
| SCHEMBL30466612 | 0.83 | MAPT (0.70) | L3MBTL1SMN1; SMN2RECQLKMT2AMEN1 | |
| SCHEMBL12635697 | 0.82 | MAPT (0.57) | L3MBTL1SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |