SCHEMBL20062853

SCHEMBL20062853

CC(C)(C)OC(=O)NCc1nc2ccccc2n1CCCS(=O)(=O)O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.55
POLB P06746 1/20 0.53
HPGD P15428 1/20 0.53
RECQL P46063 1/20 0.53
TP53 P04637 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 1/20 0.48
MAPT P10636 2/20 0.47
BRD4 O60885 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12635695 0.86 MEN1 (0.66) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL12635924 0.86 L3MBTL1 (0.57) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL12636626 0.84 L3MBTL1 (0.55) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL12634827 0.83 HTT (0.57) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL12635728 0.83 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL2016114 0.83 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL12634804 0.81 LMNA (0.66) L3MBTL1SMN1; SMN2POLBHPGDRECQL
SCHEMBL28366489 0.81 MAPT (0.70) L3MBTL1SMN1; SMN2RECQLMEN1KMT2A
SCHEMBL30466612 0.81 MAPT (0.70) L3MBTL1SMN1; SMN2RECQLMEN1KMT2A
SCHEMBL12635697 0.81 MAPT (0.57) L3MBTL1SMN1; SMN2POLBTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10220096-B2 Injectable and stable hydrogels with dynamic properties modulated by biocompatible catalysts THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-03-05 US disclosed
US-20180104348-A1 INJECTABLE AND STABLE HYDROGELS WITH DYNAMIC PROPERTIES MODULATED BY BIOCOMPATIBLE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10220096-B2 Injectable and stable hydrogels with dynamic properties modulated by biocompatible catalysts MMP1, F12, CD44 L3MBTL1 3327/4885SMN1; SMN2 2918/4885POLB 1292/4885
US-20180104348-A1 INJECTABLE AND STABLE HYDROGELS WITH DYNAMIC PROPERTIES MODULATED BY BIOCOMPATIBLE CATALYSTS MMP1, F12, CD44 L3MBTL1 3327/4885SMN1; SMN2 2918/4885POLB 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.