SCHEMBL20161314

SCHEMBL20161314

CCCCCCOC(=O)CC1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
FAAH O00519 1/20 0.41
TLR4 O00206 1/20 0.41
DGKA P23743 1/20 0.40
HTR2C P28335 1/20 0.40
GBA2 Q9HCG7 1/20 0.39
GBA1 P04062 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577836 0.88 NAAA (0.56) NAAARAD52NPSR1FAAHDGKA
SCHEMBL9257908 0.88 NAAA (0.56) NAAARAD52NPSR1FAAHDGKA
SCHEMBL20161705 0.86 MAPK1 (0.50) NAAARAD52NPSR1FAAHTLR4
SCHEMBL20161949 0.86 MAPK1 (0.50) NAAARAD52NPSR1FAAHTLR4
SCHEMBL20161669 0.82 GAA (0.38) TLR4
SCHEMBL13998382 0.77 TLR4 (0.52) TLR4DGKA
SCHEMBL18214231 0.77 GBA2 (0.48) NAAARAD52NPSR1FAAHDGKA
SCHEMBL14827529 0.76 NAAA (0.53) NAAARAD52NPSR1FAAHDGKA
SCHEMBL18214222 0.74 FUCA1 (0.34)
SCHEMBL20158784 0.73 NAAA (0.39) NAAAGBA2GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11045411-B2 Process for treating keratin materials using amide, acid or ester c-glycoside derivatives, and cosmetic composition containing same L'OREAL (FR) 2021-06-29 US disclosed
US-20180133137-A1 PROCESS FOR TREATING KERATIN MATERIALS USING AMIDE, ACID OR ESTER C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME L'OREAL (FR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180133137-A1 PROCESS FOR TREATING KERATIN MATERIALS USING AMIDE, ACID OR ESTER C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME KRT18, CUTA, GLA NAAA 232/4885RAD52 1722/4885NPSR1 2216/4885
US-11045411-B2 Process for treating keratin materials using amide, acid or ester c-glycoside derivatives, and cosmetic composition containing same KRT18, CUTA, GLA NAAA 232/4885RAD52 1722/4885NPSR1 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.