Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.35 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237862 | 0.76 | — | — | |
| SCHEMBL20547259 | 0.76 | TET3 (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL167151 | 0.76 | TET3 (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL12764449 | 0.76 | TET3 (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL20879277 | 0.74 | CTSL (0.39) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL149678 | 0.69 | — | — | |
| SCHEMBL505654 | 0.69 | ALDH1A1 (0.48) | TET3KMT2AFBXL19CXXC5KDM2B | |
| Vinyl Chloride SCHEMBL11122339 | 0.69 | TET3 (0.43) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL1591923 | 0.69 | — | — | |
| SCHEMBL20456230 | 0.69 | TEAD1 (0.39) | TET3KMT2AFBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |